To address these issues and improve farming productivity and profitability, we conducted field trials in 2018 at the Southeast Georgia Research and Education Center in Midville, Georgia to compare three different types of production practices, including UGA Recommendations for cotton production, a high input system, and a low input system. The high input system follows the practices of cotton farmers where excessive amount of nutrients and pesticide are used, where the low input system follows the practices of cotton farmers where minimum efforts were applied in applying nutrients and managing pests. A comparative analysis of these three production systems will be conducted in maintaining profitability and sustainability for cotton farmers. Our goal of this research is to improve the profitability of Georgia cotton growers, while reducing the input usage and cost. Economic analysis will be conducted by using budgeting analysis to investigate the cost and benefits of each production system. The cost of inputs and prices for cotton will be used to identify the economic profitability for each strategy.