MIC-3 Overexpression Increases Cotton Resistance to RKN and Has an Additive Effect When Combined with the Chromosome 14 Resistance QTL

My laboratory has been studying the role of the MIC gene family in mediating cotton resistance to root-knot nematode.  The MIC-3 protein was first identified as accumulating specifically within the immature galls of RKN-resistant plants having the chromosome 11 and 14 resistance QTL.  This presentation will describe the work we have done in characterizing the MIC gene family at the molecular level, the effect of MIC-3 overexpression on RKN resistance in a susceptible genetic background, and the genetic interaction between the MIC-3 overexpression construct and the chromosome 11 and 14 resistance QTL.