Cotton growers recognize that damage attributable to nematodes is often uneaqually distributed across their fields. Spatial distribution of important nematodes, for example the southern root-knot nematode, is closely tied to the texture of the soil in the field. This session has been developed to provide a very practical look at the use of site-specific application of nematicides to protect the crop and yields while at the same time managing costs of application. With site-specific applications using "zone management" strategies, costs are minimized by applying a nematicide only where needed.