9292 Invisible Proteins: Novel Delivery System For The Stabilization And Enhanced Activity Of Protein Insecticides

Tuesday, January 6, 2009
Salon H (Marriott Rivercenter Hotel)
Wednesday, January 7, 2009
Salon H (Marriott Rivercenter Hotel)
Thursday, January 8, 2009
Salon H (Marriott Rivercenter Hotel)
R. Michael Roe1, L. Jeffers1, B.W. Bissinger2, Hongyan Shen1, T. Brent Gunnoe1 and Alan Brandt3, (1)North Carolina State University, Raleigh, NC, (2)Department of Entomology, NC State University, Raleigh, NC, (3)EpaFeX, Chapel Hill, NC
Structure-activity studies were conducted with PEG-protein polymers to demonstrate the utility of this approach for reducing the degradation of insecticidal proteins by proteases and to enhance the delivery of proteins from the insect digestive system to the site of insecticidal action in the hemocoel.