Syngenta is developing pyramided transgenic VipCot™ cotton varieties that produce two insecticidal proteins derived from Bacillus thuringiensis, Vip3A and Cry1Ab. Both proteins are highly effective against Helicoverpa zea, cotton bollworm and Heliothis virescens, tobacco budworm. In 2006, field evaluations to investigate the dose status of VipCot™ were conducted in Mississippi, Louisiana and Texas using artificial infestations of H. zea and H. virescens eggs. The results of these trials and implications for resistance management will be discussed.