Small plot replicated studies were conducted in Texas, Mississippi, Missouri, Tennessee, Alabama, Georgia and South Carolina to determine the effect of mepiquat chloride and planting rates on the growth, yields and lint quality of the new PhytoGen 400 series. The primary objective was to determine if the application of mepiquat chloride in combination with 2 Roundup Ready Flex applications will provide the needed growth management when PHY 475 WRF is planted at 1X and 1/2X seeding rates. Yields, lint quality, plant mapping data and other results from these trials should provide valuable information to growers, consultants, dealers and university personnel as PhytoGen varieties become more widely planted.