Horseweed (Conyza canadensis) has been documented to be resistant to many herbicide modes of action around the world including paraquat (Gramoxone) and glyphosate (Roundup). Since 2001, glyphosate-resistant populations of horseweed have been reported in several states across the United States, including Arkansas, Tennessee, and Mississippi. The widespread adoption of glyphosate-tolerant crops and the rapid spread of glyphosate-resistant horseweed have created a need for research investigating alternative measures of control for this troublesome weed. Horseweed is commonly found in undisturbed areas and has been listed as a problem weed in conservation and no-till systems. Determining the most efficacious chemical means for controlling horseweed is imperative in reducing possible crop yield losses due to competition. In studies conducted at the Delta Research and Extension Center in Stoneville, MS spring burndowns including glyphosate, paraquat and glufosinate (Ignite) were compared alone and with several tank-mix partners some of which included dicamba (Clarity). Glyphosate alone (@ 0.77 lbs ae/a) gave 63% control and paraquat alone (@ 0.75 lbs ai/a) gave only 55% control; however, the addition of dicamba (@ 0.25 lbs ai/a) improved control to 90% and 84% respectively. Excellent control of horseweed (92%) was seen with glufosinate alone @ 0.42 lbs ai/a.