Belonging to a new chemical class named tetronic acids, OBERON 2 SC is a new insecticide/miticide for foliar application in annual crops against all important whitefly, mite and psyllid species. OBERON is active against all mite development stages including eggs (however mite juvenile stages are often more susceptible than adults). OBERON is also highly effective against whitefly and psyllid nymphs, with a significant effect on the otherwise difficult to control pupal stage. The mode of action of OBERON has been characterized as lipid biosynthesis inhibition (LBI). OBERON interferes with insect/mite lipogenesis by preventing proper biosynthesis of fatty acids and their subsequent biochemical derivatives. This active ingredient has shown no cross-resistance to conventional insecticides/miticides. OBERON received federal registration in May 2005 and is now registered in 48 states. While not only being the introduction year for OBERON, 2005 also was a very heavy mite year. OBERON acceptance exceeded expectations with very good results and equal or better efficacy than comparable standards in most areas of the country. Mid-south cotton results from demo plots indicate that this area of the country offers some specific challenges but OBERON, when applied at the correct timing and with good coverage, offers effective mite control.