Studes conducted from 2002 to 2005 have found no simple solutions to Palmer amaranth management. Simply adding a preemergence herbicide, or a postemergence tank mixture or changing a post-directed treatment to a glyphosate-based program does not guarantee acceptable control. Fomesafen (Reflex) has been an above-average preemergence treatment; however, in other studies, occasional, severe crop injury has occurred. Metolachlor-glyphosate postemergence tank mixtures often improve Palmer amaranth control, but only if an activating rainfall moves the metolachlor to the soil. Slight differences exist in the efficacy of post-directed treatments; however, all provide acceptable control if applied in a timely fashion, and all provide unacceptable control if applied late. Adding propazine (Miloguard) to glyphosate has provided significant improvements in Palmer amaranth control, however this herbicide has never been registered for cotton, nor is it being manufactured for any crop.