Stink bugs have become a major pest in cotton in the SE USA since boll weevil eradication and the widespread use of Bt cultivars have greatly reduced the number of broad spectrum insecticide applications. Stink bugs damage bolls by piercing boll walls and feed on developing seeds. At the same time, textile manufacturers have raised concerns that mill performance of cotton has been compromised by transgenic technology. Our objectives were to 1) determine the influence of stink bugs on textile mill performance; and 2) evaluate whether cotton textile mill performance is influenced by transgenic technology. Stoneville 474, Stoneville 4691B, Stoneville 4793RR, Stoneville 4892BR, Stoneville BXN 47, and Stoneville BXN 49B were grown in randomized plots with and without insecticide applications for stink bugs in 2002 and 2003. Harvested cotton was tested and processed in the Pilot Spinning Laboratory at the Cotton Quality Research Station in Clemson, South Carolina. Cotton spinning efficiency, yarn quality, and fabric imperfections (white specks) were measured.