Spatially variable applications of plant growth regulators and cotton defoliants were demonstrated to Louisiana cotton producers during the 2005 growing season. Variable rate applications were based on the normalized difference vegetative index for the field at the time of application. Producers, or their representative, were provided with field images of the NDVI. The producer would then select a rate structure for each application. Variable rate treatments were compared with a blanket or broadcast application (rate provided by producer). All applications were applied using commercially available aerial applicators. Savings in plant growth regulator costs and defoliants were minimal compared to the broadcast application.