Field experiments were conducted in 200-2005 cotton seasons in Minia Governorate, Middle Egypt to evaluate the role of Tricogramma evanescens and certain bio-products (Agrin and Spintor) in reducing infestation with cotton key pests throughout the weekly infestation level of cotton leaves and green bolls. Results indicated that direct and insignificant effects against cotton bollworms and cotton leafworm as well as indirect effect against the sucking pests.