India has the largest national production area for cotton in the world but on average has some of the lowest yields per area. It has many diverse production segments ranging from subsistence to high technology GM hybrids. Dow AgroSciences has a long history of exporting and marketing products to the Indian cotton farmers and is the leading insect solution company today. Products targeting bollworms (Helicoverpa armigera, Spodoptera litura and Earias vittella) include chlorpyrifos, chlorpyrifos + cypermethrin, and spinosad. WideStrike^TM is a new generation stacked trait that expresses Cry1F and Cry1Ac proteins in cotton. WideStrike^TM varieties were grown commercially on a limited scale in the United States during 2005. Efficacy of WideStrike^TM proteins against major cotton bollworms in India was studied. Initial observations from these studies and the potential for WideStrike^TM in India will be discussed.