The southern root-knot nematode, Meloidogyne incognita, is the most widespread pathogenic nematode of cotton in Georgia and accounts for severe losses each year. Management of the southern root-knot nematode involves a combination of crop rotation with non-susceptible host crops, such as peanuts, cultural practices, such as sub-soiling and irrigation, to reduce stress on the cotton plant, and the use of nematicides. The objectives of this study are to evaluate the effectiveness of standard nematicides, such as aldicarb (Temik 15G) and 1,3 dichloropropene (Telone II), and two new materials(Avicta and N-Hibit).